Science designed to be challenged.
CoreX is built for scientific scrutiny: defined use cases, documented protocols, quality-controlled biology, auditable data systems, and transparent limitations. Biological intelligence is only valuable if it can be inspected, questioned, reproduced, and improved.
Blinded studies. Defined use cases. Inspectable evidence.
CoreX deploys the Quris-AI Bio-AI platform for sovereign, population-specific medicine programs. In defined drug-induced liver injury (DILI) benchmarks and blinded prospective studies, the platform has demonstrated performance against conventional biology-only and AI-only approaches. Full study designs, compound sets, comparator methods, confidence intervals, and limitations are available to qualified partners under NDA.
Platform evidence shown in defined DILI and blinded prospective study contexts. Not a general claim across all diseases, medicines, organs, or populations.
Liver-toxicity (DILI) prediction in a retrospective benchmark, versus 80% for 2D biology and 76% for 3D biology alone.
Quris-AI platform evidenceOn the same DILI benchmark, versus 25% for 2D biology and 50% for 3D biology alone.
Quris-AI platform evidenceIn independent blinded prospective studies, versus 68% for AI alone and 63% for biology alone.
Quris-AI platform evidenceIn one program, the same platform flagged a safety signal in a major drug candidate that standard preclinical models did not catch.
"This technology flags drug toxicity that all our models completely missed."CAMS 2024 · blinded validation study
Evaluated in independent, blinded prospective studies with leading global pharmaceutical partners.
Metrics reflect defined contexts of use, such as liver-toxicity (DILI) prediction. Full study designs, compound sets, comparator methods, confidence intervals, and limitations are available to qualified partners under NDA.
Every result, under glass.
Each result is shown with its context of use, study type, comparator, and its limitation. Evidence is only useful if you can see its edges.
What each capability is for, and what it is not.
A model is never validated in general. It is validated for a defined context of use: a specific question, under specific conditions, with a stated boundary.
DILI / liver toxicity
- StatusQualified partner programs
- EvidenceDILI benchmarks and blinded study data
- OutputToxicity-risk signal
- Not claimedBroad safety prediction across all organs or mechanisms
PK / exposure-response
- StatusDefined programs
- EvidenceInternal and partner program data
- OutputExposure and dose-response insight
- Not claimedClinical dosing recommendation without additional evidence
Population cohort modeling
- StatusGoverned programs
- EvidenceIHLAD and CoreX deployment
- OutputVariation across selected cohorts
- Not claimedUniversal prediction for every individual
Multi-organ response
- StatusResearch-stage
- EvidenceInternal and exploratory work
- OutputExploratory tissue-response data
- Not claimedValidated whole-body clinical prediction
From biology to population intelligence.
- 01
Biology
Living donor-specific models.
- 02
Assay
Controlled organ-on-chip and organoid response systems.
- 03
Dataset
Structured biological response signals.
- 04
Model
Governed AI trained on biological response.
- 05
Decision support
Partner insight for defined use cases.
- 06
Population intelligence
Compounding evidence across cohorts.
Defined context of use
Every claim is tied to a specific scientific or development use case.
Protocol discipline
Clear endpoints, inclusion criteria, controls, and analysis plans.
Biological quality control
Documented characterization, acceptance criteria, and batch controls.
Model governance
Data provenance, version control, leakage prevention, and auditability.
| Capability | Status | Public wording |
|---|---|---|
| Drug toxicity modeling | Qualified programs | Available for qualified partner programs |
| Pharmacokinetic modeling | Defined programs | Available under defined programs |
| Population cohort modeling | Governed programs | Available through governed population programs |
| Multi-organ response | Research-stage | Research-stage / partner development |
| Regenerative applications | Future research | Not offered as a clinical therapy |
Capability labels are intentionally high-level. Technical validation materials, study design, and context-specific performance data are available to qualified partners under appropriate confidentiality frameworks.
CAMS 2024 · blinded validation study