A living, continuously expanding biobank of iPSC-derived organoids representing real populations.
PBLO powers population-specific medicine and sovereign pharmacoequity — ensuring every therapy is optimized for the people it serves.
Open source for sovereign users.

The Bio-Bank That Thinks

At the foundation of PBLO is a national iPSC biobank — a continuously growing repository of stem cells derived from real, diverse populations.

From these living source cells, we can endlessly differentiate new tissues and organoids, regenerating Bio-Avatars that act as miniature replicas of human biology.
 

Each Bio-Avatar captures the complexity of its donor’s genetic and metabolic signature, allowing us to study how real bodies — across demographics — respond to therapies, toxins, and environments.
 

From Patient-on-a-Chip to Population-on-Chip

Our high-throughput Chip-on-Chip system automates the testing of thousands of compounds across these Bio-Avatars.

Nano-sensors continuously track cellular and organ-level responses, feeding a learning loop that trains AI models to predict efficacy, toxicity, and dose response with population-specific precision.
 

Where traditional trials observe a few hundred people, PBLO learns from thousands of living biological replicas — a digital-biological cohort in perpetual evolution.
 

Training AI on Humanity’s True Diversity

By spanning diverse ethnic, genomic, and environmental profiles, PBLO enables AI to model how different populations metabolize and respond to drugs.

This data forms the backbone of precision dosing and demographic-specific drug design — unlocking safer, more effective therapies for every population group.
 

Sovereign Infrastructure for Pharmacoequity

PBLO is designed as open infrastructure for sovereign use.
Nations and health systems can build their own population-representative bio-libraries, ensuring data ownership, local AI training, and therapeutic development that directly benefits their citizens.

This is the foundation of sovereign pharmacoequity — healthcare built by, and for, the populations it serves.